mtrB [2017-8-11 16:0:3]

tryptophan operon RNA-binding attenuation protein (TRAP), controls the RNA switch in front of genes involved in biosynthesis and acquisition of tryptophan

Locus: BSU22770

Isoelectric point: 7.33

Molecular weight: 8.19 kDa

Protein length: 75 aa

Gene length: 225 bp

Function: regulation of tryptophan biosynthesis(and translation) attenuation in the trp operon;repression of the folate operon

Product: tryptophan operon RNA-binding attenuation protein (TRAP)

Essential: no

Synonyms

Genomic Context

Loading

Categories containing this gene/protein

• Metabolism → Amino acid/ nitrogen metabolism → Biosynthesis/ acquisition of amino acids → Biosynthesis/ acquisition of aromatic amino acids
• Information processing → Regulation of gene expression → Transcription factors and their control → Transcription factors/ other
• Information processing → Regulation of gene expression → RNA binding regulators

Gene

Coordinates: 2,384,534 → 2,384,761

The protein

Protein family

• prpD family (according to Swiss-Prot)

Effectors of protein activity

• binding of tryptophan results RNA binding and thus in transcription termination

Structure

• 3AQD, 1WAP (complex with L-tryptophan), 2ZP9 (complex with RtpA)

Expression and Regulation

Operons

• Genes: folE-mtrB
  Description: PubMed

  Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon

  Regulation

  • constitutive PubMed

References

Reviews

Loading

Original Publications

Loading